Graduate Students: The Raleigh Lab places a premium on education, mentorship, and training. Graduate student rotations are always available. Projects are individualized according to students' experiences and interests, and include, but are not limited to, identification and characterization of genes involved in brain tumor pathogenesis using biochemical and molecular techniques, informatic analysis of clinical and sequencing data from human samples, mouse genetic or patient derived xenograft models, or a combination of all of the above. We currently have 1 position available for a graduate student to complete their doctoral dissertation in the Raleigh lab.
Postdoctoral Scholars:
The Raleigh Lab at the University of California San Francisco (UCSF) has 1 available position for a postdoctoral scholar. Research in the Raleigh lab is focused on understanding the genomic, biochemical, and cellular drivers of tumor heterogeneity and evolution. Our team of basic scientists, bioinformaticians, and clinicians integrate human samples with diverse evolutionary and preclinical models to study cancer predisposition, tumorigenesis, and treatment resistance. In addition to showing how tumors develop and respond to therapy, our studies have elucidated mechanisms through neurofibromatosis tumor suppressor genes, epigenetic regulators, and the Hedgehog pathway that drive developmental patterning and stem cell homeostasis.
The Raleigh Lab is located at the UCSF Mission Bay Medical Center in the Brain Tumor Center on the 4th floor of the Helen Diller Family Comprehensive Cancer Center Research Building. Dr. Raleigh is a Physician Scientist in the Departments of Radiation Oncology, Neurological Surgery, and Pathology at UCSF. He is the Michael McDermott, MD, Professor and the Director of the Preclinical Therapeutics Core in the UCSF Brain Tumor Center. Eighty percent of his time is dedicated to research, and the postdoctoral position that is available is focused on improving understanding of meningioma biology and treatments for patients with meningioma. All prior trainees in the Raleigh Lab have matriculated to successful independent careers in science and/or medicine.
Highly motivated individuals with doctoral training from broad scientific backgrounds are encouraged to apply. Mentorship and collaborative multidisciplinary science are essential in the Raleigh Lab, and candidates should have an aptitude for mentorship of junior lab members. Potential projects include investigations of inter-tumor heterogeneity (PMID: 35534562, 36227281, 29590631), intra-tumor heterogeneity (PMID: 32968068, 32023450, 35759011), predictive biomarkers (PMID: 37944590, 37963810, 38057502), signaling mechanisms (PMID: 30340023, 29202464, 38216572), and cancer stem cells (PMID: 31901251, 36067288, 38742767) using diverse experimental approaches, including functional genomic techniques (PMID: 33476305, 38216587) and spatial genomics (PMID: 38760638).
To apply, please send CV and cover letter to [email protected]. The Raleigh Lab website and additional information can be found at https://raleighlab.ucsf.edu/raleigh-laboratory.
How to Help: We rely on private philanthropy to support our research and implementation in our clinical programs. Your generosity will enable us to expand our programs and further improve their quality resulting in advances in applying the computational sciences towards improving the delivery of cancer care and the outcomes for patients with cancer. To help ensure our programs continue, please contact Alan Taniguchi, Operations Manager, at [email protected] or 415-353-9880. Thank you!